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Article

Exome-based Variant Detection in Core Promoters.

Scientific reports - 28 Jul 2016

Kim Yeong C, Cui Jian, Luo Jiangtao, Xiao Fengxia, Downs Bradley, Wang San Ming

Abstract excerpt

Core promoter controls the initiation of transcription. Core promoter sequence change can disrupt transcriptional regulation, lead to impairment of gene expression and ultimately diseases. Therefore, comprehensive characterization of core promoters is essential to understand normal and abnormal gene expression in biomedical studies. Here we report the development of EVDC (Exome-based Variant Detection in Core...

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Identifiers

PMID: 27464681
DOI: 10.1038/srep30716
PMCID: PMC4964598

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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