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Article

HIV-1 Vpr increases HCV replication through VprBP in cell culture.

Virus research - 2 Sept 2016

Yan Yanling, Huang Fang, Yuan Ting, Sun Binlian, Yang Rongge

Abstract excerpt

Coinfection of human immunodeficiency virus (HIV) and hepatitis C virus (HCV) occurs at a high frequency, in which HIV shows a promotion of HCV-derived liver diseases. However, the mechanism of how this occurs is not well understood. Our previous work has demonstrated that the HIV-1 accessory protein Vpr enhances HCV RNA replication in cell culture. Because Vpr performs most of its functions through host protein...

Read the complete abstract on PubMed

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Share to Coinfection
Share to Gene Knockdown Techniques
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hepatitis C

Share to Microbial Interactions

Share to Ubiquitin-Protein Ligases

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Share to vpr Gene Products, Human Immunodeficiency Virus

Source

Identifiers

PMID: 27460548
DOI: 10.1016/j.virusres.2016.07.007

Genes

DCAF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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