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Article

The functions of the HIV1 protein Vpr and its action through the DCAF1·DDB1·Cullin4 ubiquitin ligase

30 Mar 2010

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 20347598
DOI: 10.1016/j.cyto.2010.02.018

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Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

The functions of the HIV1 protein Vpr and its action through the DCAF1·DDB1·Cullin4 ubiquitin ligasePMID 20347598Read ↗

Hijacking of the Ubiquitin/Proteasome Pathway by the HIV Auxiliary ProteinsSemantic proximity Read ↗

Assembly with the Cul4A-DDB1DCAF1 ubiquitin ligase protects HIV-1 Vpr from proteasomal degradation.Semantic proximity Read ↗

The Human Immunodeficiency Virus Type 2 Vpx Protein Usurps the CUL4A-DDB1 DCAF1 Ubiquitin Ligase To Overcome a Postentry Block in Macrophage InfectionSemantic proximity Read ↗

HIV-1 Vpr-induced DNA damage activates NF-κB through ATM-NEMO independent of cell cycle arrestSemantic proximity Read ↗

DCAF1 (VprBP): emerging physiological roles for a unique dual-service E3 ubiquitin ligase substrate receptorSemantic proximity Read ↗

Vpr Targets TET2 for Degradation by CRL4VprBP E3 Ligase to Sustain IL-6 Expression and Enhance HIV-1 ReplicationSemantic proximity Read ↗

HIV-1 Vpr degrades the HLTF DNA translocase in T cells and macrophagesSemantic proximity Read ↗

HIV-1 Vpr-induced DNA damage activates NF-κB through ATM-NEMO independent of cell cycle arrestSemantic proximity Read ↗

Illuminating the Role of Vpr in HIV Infection of Myeloid CellsSemantic proximity Read ↗

HIV1-viral protein R (Vpr) mutations: associated phenotypes and relevance for clinical pathologies.Semantic proximity Read ↗

HIV Vpr modulates the host DNA damage response at two independent steps to damage DNA and repress double-strand DNA break repairSemantic proximity Read ↗

The HIV-1 protein Vpr targets the endoribonuclease Dicer for proteasomal degradation to boost macrophage infectionSemantic proximity Read ↗

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