Article
Circular RNAs-one of the enigmas of the brain.
Neurogenetics - 1 Jan 2017
Filippenkov Ivan B, Kalinichenko Eugene O, Limborska Svetlana A, Dergunova Lyudmila V
Abstract excerpt
Circular RNAs (circRNAs) provide a new and relatively unexplored class of noncoding RNAs that are predominantly found in mammalian cells. In this review, we present the latest data regarding the structural organization, possible mechanisms of synthesis, and functions of circRNAs. These transcripts were isolated as an RNA fraction that was resistant to RNase R treatment, which selectively destroys the linear forms...
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