Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Sensitivity of Allelic Divergence to Genomic Position: Lessons from the Drosophila tan Gene.

G3 (Bethesda, Md.) - 8 Sept 2016

John Alisha V, Sramkoski Lisa L, Walker Elizabeth A, Cooley Arielle M, Wittkopp Patricia J

Abstract excerpt

To identify genetic variants underlying changes in phenotypes within and between species, researchers often utilize transgenic animals to compare the function of alleles in different genetic backgrounds. In Drosophila, targeted integration mediated by the ΦC31 integrase allows activity of alternative alleles to be compared at the same genomic location. By using the same insertion site for each transgene, position...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animals, Genetically Modified
Share to Chromosomal Proteins, Non-Histone

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drosophila

Share to Drosophila Proteins

Share to Genome, Insect

Share to Integrases

Share to Species Specificity

Share to Transgenes

Source

Open in PubMed Open full text

Identifiers

PMID: 27449514
DOI: 10.1534/g3.116.032029
PMCID: PMC5015952

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Sensitivity of Allelic Divergence to Genomic Position: Lessons from the Drosophila tan Gene.PMID 27449514Read ↗

Site-specific transformation of Drosophila via phiC31 integrase-mediated cassette exchange.Semantic proximity Read ↗

Intraspecific polymorphism to interspecific divergence: genetics of pigmentation in Drosophila.Semantic proximity Read ↗

Genetic and Transgenic Reagents for Drosophila simulans, D. mauritiana, D. yakuba, D. santomea, and D. virilis.Semantic proximity Read ↗

The Drosophila gene disruption project: progress using transposons with distinctive site specificities.Semantic proximity Read ↗

Genomics of natural populations: Evolutionary forces that establish and maintain gene arrangements in Drosophila pseudoobscura.Semantic proximity Read ↗

Mapping Drosophila mutations with molecularly defined P element insertions.Semantic proximity Read ↗

Inversion polymorphisms and nucleotide variability in Drosophila.Semantic proximity Read ↗

Exploiting position effects and the gypsy retrovirus insulator to engineer precisely expressed transgenes.Semantic proximity Read ↗

Pupariation site preference within and between Drosophila sibling species.Semantic proximity Read ↗

Evidence for recurrent paralogous gene conversion and exceptional allelic divergence in the Attacin genes of Drosophila melanogaster.Semantic proximity Read ↗

The relationship between allozyme and chromosomal polymorphism inferred from nucleotide variation at the Acph-1 gene region of Drosophila subobscura.Semantic proximity Read ↗

Nucleotide variation in the triosephosphate isomerase (Tpi) locus of Drosophila melanogaster and Drosophila simulans.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.