Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

NaLi-H1: A universal synthetic library of humanized nanobodies providing highly functional antibodies and intrabodies

19 Jul 2016

Abstract excerpt

In vitro selection of antibodies allows to obtain highly functional binders, rapidly and at lower cost. Here, we describe the first fully synthetic phage display library of humanized llama single domain antibody (NaLi-H1: Nanobody Library Humanized 1). Based on a humanized synthetic single domain antibody (hs2dAb) scaffold optimized for intracellular stability, the highly diverse library provides high affinity...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Glycosylation and Glycoproteins Research
Share to Monoclonal and Polyclonal Antibodies Research
Share to RNA and protein synthesis mechanisms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 27434673
DOI: 10.7554/elife.16228

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

NaLi-H1: A universal synthetic library of humanized nanobodies providing highly functional antibodies and intrabodiesPMID 27434673Read ↗

Design, construction, and characterization of a large synthetic human antibody phage display librarySemantic proximity Read ↗

A Highly Functional Synthetic Phage Display Library Containing over 40 Billion Human Antibody ClonesSemantic proximity Read ↗

Designing Human Antibodies by Phage DisplaySemantic proximity Read ↗

Current perspectives on the preparation of efficient and effective fully synthetic human single domain antibody phage display librariesSemantic proximity Read ↗

Design of synthetic antibody librariesSemantic proximity Read ↗

Discovery of diverse and functional antibodies from large human repertoire antibody librariesSemantic proximity Read ↗

Development, High-Throughput Profiling, and Biopanning of a Large Phage Display Single-Domain Antibody LibrarySemantic proximity Read ↗

Synthetic single domain antibodies for the conformational trapping of membrane proteinsSemantic proximity Read ↗

Generation and analyses of human synthetic antibody libraries and their application for protein microarraysSemantic proximity Read ↗

Phage display antibody libraries: A robust approach for generation of recombinant human monoclonal antibodiesSemantic proximity Read ↗

Creation of the large and highly functional synthetic repertoire of human VH and Vκ domain antibodies.Semantic proximity Read ↗

A toolbox of nanobodies developed and validated for diverse neuroscience research applicationsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.