Article
An evaluation of logic regression-based biomarker discovery across multiple intergenic regions for predicting host specificity in Escherichia coli.
Molecular phylogenetics and evolution - 1 Oct 2016
Zhi Shuai, Li Qiaozhi, Yasui Yutaka, Banting Graham, Edge Thomas A, Topp Edward, McAllister Tim A, Neumann Norman F
Abstract excerpt
Several studies have demonstrated that E. coli appears to display some level of host adaptation and specificity. Recent studies in our laboratory support these findings as determined by logic regression modeling of single nucleotide polymorphisms (SNP) in intergenic regions (ITGRs). We sought to determine the degree of host-specific information encoded in various ITGRs across a library of animal E. coli isolates...
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