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Article

Molecular cloning and functional characterization of porcine E74-like factor 4 (ELF4).

Developmental and comparative immunology - 1 Dec 2016

Shi Yanling, Wang Dang, Zhu Xinyu, Wu Qiong, Chen Huanchun, Xiao Shaobo, Fang Liurong

Abstract excerpt

E74-like factor 4 (ELF4) is a novel transcription factor that initiates transcription of type I interferon (IFN) genes to control diverse pathogens. Here, porcine ELF4 (poELF4) was cloned and its role in type I IFN signaling was investigated in different porcine cell lines. Full-length cDNA of poELF4 encodes 663 amino acid residues and ectopic expression of poELF4 significantly induced IFN-β production....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 27426928
DOI: 10.1016/j.dci.2016.07.005

Genes

ELF4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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