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Hesperetin Inhibits Porcine Reproductive and Respiratory Syndrome Virus Replication by Downregulating the P38/JUN/FOS Pathway In Vitro

18 Feb 2025

Abstract excerpt

Porcine reproductive and respiratory syndrome virus (PRRSV) is a persistent pathogen that causes significant economic losses to the global swine industry. Commercial vaccines provide only partial protection, and no effective therapeutic treatments are currently available. In this study, we demonstrate that hesperetin (Hst), a flavonoid glycoside derived from orange and tangerine peels, inhibits PRRSV replication...

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PMID: 40005815
DOI: 10.3390/microorganisms13020450

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