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Article

Extracellular matrix composition defines an ultra-high-risk group of neuroblastoma within the high-risk patient cohort

14 Jul 2016

Abstract excerpt

BACKGROUND: Although survival for neuroblastoma patients has dramatically improved in recent years, a substantial number of children in the high-risk subgroup still die. METHODS: We aimed to define a subgroup of ultra-high-risk patients from within the high-risk cohort. We used advanced morphometric approaches to quantify and characterise blood vessels, reticulin fibre networks, collagen type I bundles, elastic...

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PMID: 27415013
DOI: 10.1038/bjc.2016.210

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