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Article

FOXL2 Is an Essential Activator of SF-1-Induced Transcriptional Regulation of Anti-Müllerian Hormone in Human Granulosa Cells.

PloS one - 1 Jan 2016

Jin Hanyong, Won Miae, Park Si Eun, Lee Seunghwa, Park Mira, Bae Jeehyeon

Abstract excerpt

Anti-Müllerian hormone (AMH) is required for proper sexual differentiation by regulating the regression of the Müllerian ducts in males. Recent studies indicate that AMH could be an important factor for maintaining the ovarian reserve. However, the mechanisms of AMH regulation in the ovary are largely unknown. Here, we provide evidence that AMH is an ovarian target gene of steroidogenic factor-1 (SF-1), an orphan...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Forkhead Box Protein L2

Share to Forkhead Transcription Factors

Share to Gene Expression Regulation

Share to Granulosa Cells

Share to Promoter Regions, Genetic

Share to Steroidogenic Factor 1

Source

Open in PubMed Open full text

Identifiers

PMID: 27414805
DOI: 10.1371/journal.pone.0159112
PMCID: PMC4944948

Genes

AMH
FOXL2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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