Article
The murine winged-helix transcription factor Foxl2 is required for granulosa cell differentiation and ovary maintenance.
Development (Cambridge, England) - 1 Feb 2004
Schmidt Dirk, Ovitt Catherine E, Anlag Katrin, Fehsenfeld Sandra, Gredsted Lars, Treier Anna-Corina, Treier Mathias
Abstract excerpt
Human Blepharophimosis/ptosis/epicanthus inversus syndrome (BPES) type I is an autosomal dominant disorder associated with premature ovarian failure (POF) caused by mutations in FOXL2, a winged-helix/forkhead domain transcription factor. Although it has been shown that FOXL2 is expressed in adult...
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