Article
Lysophosphatidic acid does not cause blood/lymphatic vessel plasticity in the rat mesentery culture model.
Physiological reports - 1 Jul 2016
Sweat Richard S, Azimi Mohammad S, Suarez-Martinez Ariana D, Katakam Prasad, Murfee Walter L
Abstract excerpt
Understanding the mechanisms behind endothelial cell identity is crucial for the goal of manipulating microvascular networks. Lysophosphatidic acid (LPA) and serum stimulation have been suggested to induce a lymphatic identity in blood endothelial cells in vitro. The objective of this study was to determine if LPA or serum induces blood-to-lymphatic vessel phenotypic transition in microvascular networks. The rat...
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