Article
VEGF-C induced angiogenesis preferentially occurs at a distance from lymphangiogenesis.
Cardiovascular research - 1 May 2008
Benest Andrew V, Harper Steven J, Herttuala Seppo Yla, Alitalo Kari, Bates David O
Abstract excerpt
AIMS: Vascular endothelial growth factor-C (VEGF-C) has been shown to stimulate both angiogenesis and lymphangiogenesis in some but not all models where VEGF-C is over-expressed. Our aim was to investigate the interaction between lymphangiogenesis and angiogenesis in adult tissues regulated by VEGF-C and identify evidence of polarized growth of lymphatics driven by specialized cells at the tip of the growing...
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