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Personalized and targeted therapy of esophageal squamous cell carcinoma: an update

11 Jul 2016

Abstract excerpt

Esophageal squamous cell carcinoma (ESCC) is a deadly disease that requires extensive research. In this review, we update recent progress in the research area of targeted therapy for ESCC. SOX2 and its associated proteins (e.g., ΔNP63α), which regulate lineage survival of ESCC cells, are proposed as therapeutic targets. It is believed that targeting the lineage-survival mechanism may be more effective than...

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PMID: 27399176
DOI: 10.1111/nyas.13144

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