Article
Integrative radiogenomic analysis for genomic signatures in glioblastomas presenting leptomeningeal dissemination.
Medicine - 1 Jul 2016
You Hye Jin, Park Ho-Young, Kim Jinkuk, Lee In-Hee, Seol Ho Jun, Lee Jung-Il, Kim Sung Tae, Kong Doo-Sik, Nam Do-Hyun
Abstract excerpt
Despite therapeutic advances, the prognosis for glioblastoma (GBM) remains poor. In particular, leptomeningeal dissemination (LMD) has a dismal prognosis. The aim of this study was to identify tumor molecular phenotype, which has a great propensity to develop LMD. Between May 2004 and December 2012, a total of 145 GBM tumor samples were obtained from data registry. A total of 20 of the 145 patients with GBM were...
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