Article
Emerging Role for RBM20 and its Splicing Substrates in Cardiac Function and Heart Failure.
Current pharmaceutical design - 1 Jan 2016
Ma Jipeng, Lu Linhe, Guo Wei, Ren Jun, Yang Jian
Abstract excerpt
Heart failure is one of the devastating public health problems with high mortality. Among various contributing factors for heart failure, severe dilated cardiomyopathy is the most common indication for cardiac transplantation. Recent evidence revealed that RBM20 mutation represents one main cause for familial dilated cardiomyopathy with a 3% prevalence in all forms of dilated cardiomyopathy. Further scrutiny of...
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