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RBM20-Related Cardiomyopathy: Current Understanding and Future Options

11 Sept 2021

Abstract excerpt

Splice regulators play an essential role in the transcriptomic diversity of all eukaryotic cell types and organ systems. Recent evidence suggests a contribution of splice-regulatory networks in many diseases, such as cardiomyopathies. Adaptive splice regulators, such as RNA-binding motif protein 20 (RBM20) determine the physiological mRNA landscape formation, and rare variants in the RBM20 gene explain up to 6%...

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PMID: 34575212
DOI: 10.3390/jcm10184101

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