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Article

Redox mechanisms in age-related lung fibrosis.

Redox biology - 1 Oct 2016

Kurundkar Ashish, Thannickal Victor J

Abstract excerpt

Redox signaling and oxidative stress are associated with tissue fibrosis and aging. Aging is recognized as a major risk factor for fibrotic diseases involving multiple organ systems, including that of the lung. A number of oxidant generating enzymes are upregulated while antioxidant defenses are deficient with aging and cellular senescence, leading to redox imbalance and oxidative stress. However, the precise...

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Identifiers

PMID: 27394680
DOI: 10.1016/j.redox.2016.06.005
PMCID: PMC4943089

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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