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A Model Study of In Silico Proficiency Testing for Clinical Next-Generation Sequencing.

Archives of pathology & laboratory medicine - 1 Oct 2016

Duncavage Eric J, Abel Haley J, Merker Jason D, Bodner John B, Zhao Qin, Voelkerding Karl V, Pfeifer John D

Abstract excerpt

CONTEXT: -Most current proficiency testing challenges for next-generation sequencing assays are methods-based proficiency testing surveys that use DNA from characterized reference samples to test both the wet-bench and bioinformatics/dry-bench aspects of the tests. Methods-based proficiency testing surveys are limited by the number and types of mutations that either are naturally present or can be introduced into...

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PMID: 27388684
DOI: 10.5858/arpa.2016-0194-CP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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