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Targeting MAPK Signaling in Age-Related Macular Degeneration

1 Jan 2016

Abstract excerpt

Age-related macular degeneration (AMD) is a major cause of irreversible blindness affecting elderly people in the world. AMD is a complex multifactorial disease associated with demographic, genetics, and environmental risk factors. It is well established that oxidative stress, inflammation, and apoptosis play critical roles in the pathogenesis of AMD. The mitogen-activated protein kinase (MAPK) signaling pathways...

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PMID: 27385915
DOI: 10.4137/oed.s32200

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