Article
Genetic predisposition to pediatric myeloid malignancies.
[Rinsho ketsueki] The Japanese journal of clinical hematology - 1 Jun 2016
Muramatsu Hideki
Abstract excerpt
Various genetic disorders are known to be associated with cancer predisposition. For example, children with Down syndrome are predisposed to developing acute myeloid leukemia, and those with RASopathies, such as Noonan syndrome, are predisposed to juvenile myelomonocytic leukemia. To date, more than 250 diseases or syndromes have been reported to be associated with the development of pediatric cancers. Recently,...
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