Article
Update on Recommendations for Surveillance for Children with Predisposition to Hematopoietic Malignancy.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Oct 2024
Maese Luke D, Wlodarski Marcin W, Kim Sun Young, Bertuch Alison A, Bougeard Gaelle, Chang Vivian Y, Godley Lucy A, Khincha Payal P, Kuiper Roland P, Lesmana Harry, McGee Rose B, McReynolds Lisa J, Meade Julia, Plon Sharon E, Savage Sharon A, Scollon Sarah R, Scott Hamish S, Walsh Michael F, Nichols Kim E, Porter Christopher C
Abstract excerpt
Children harboring certain germline gene variants have an increased risk of developing myelodysplastic syndrome (MDS) and other hematopoietic malignancies (HM), such as leukemias and lymphomas. Recent studies have identified an expanding number of these predisposition genes, with variants most prevalent in children with MDS but also found in children with other HM. For some hematopoietic malignancy...
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