Risk of Lung Cancer Associated with COPD Phenotype Based on Quantitative Image Analysis.

doi:10.1158/1055-9965.EPI-16-0176

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Article

Risk of Lung Cancer Associated with COPD Phenotype Based on Quantitative Image Analysis.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Sept 2016

Schwartz Ann G, Lusk Christine M, Wenzlaff Angela S, Watza Donovan, Pandolfi Stephanie, Mantha Laura, Cote Michele L, Soubani Ayman O, Walworth Garrett, Wozniak Antoinette, Neslund-Dudas Christine, Ardisana Amy A, Flynn Michael J, Song Thomas, Spizarny David L, Kvale Paul A, Chapman Robert A, Gadgeel Shirish M

Abstract excerpt

BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a risk factor for lung cancer. This study evaluates alternative measures of COPD based on spirometry and quantitative image analysis to better define a phenotype that predicts lung cancer risk. METHODS: A total of 341 lung cancer cases and 752 volunteer controls, ages 21 to 89 years, participated in a structured interview, standardized CT scan, and...

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PMID: 27383774
DOI: 10.1158/1055-9965.EPI-16-0176
PMCID: PMC5010488

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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