Article
C-Terminal Alpha-1 Antitrypsin Peptide: A New Sepsis Biomarker with Immunomodulatory Function.
Mediators of inflammation - 1 Jan 2016
Blaurock Nancy, Schmerler Diana, Hünniger Kerstin, Kurzai Oliver, Ludewig Katrin, Baier Michael, Brunkhorst Frank Martin, Imhof Diana, Kiehntopf Michael
Abstract excerpt
Systemic inflammatory response syndrome (SIRS) is a life threatening condition and the leading cause of death in intensive care units. Although single aspects of pathophysiology have been described in detail, numerous unknown mediators contribute to the progression of this complex disease. The aim of this study was to elucidate the pathophysiological role of CAAP48, a C-terminal alpha-1 antitrypsin fragment, that...
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