Article
Mapping the subcellular mechanical properties of live cells in tissues with fluorescence emission-Brillouin imaging.
Science signaling - 5 Jul 2016
Elsayad Kareem, Werner Stephanie, Gallemí Marçal, Kong Jixiang, Sánchez Guajardo Edmundo R, Zhang Lijuan, Jaillais Yvon, Greb Thomas, Belkhadir Youssef
Abstract excerpt
Extracellular matrices (ECMs) are central to the advent of multicellular life, and their mechanical properties are modulated by and impinge on intracellular signaling pathways that regulate vital cellular functions. High spatial-resolution mapping of mechanical properties in live cells is, however, extremely challenging. Thus, our understanding of how signaling pathways process physiological signals to generate...
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