Article
Screening for genotypic and phenotypic variations in CYP450 activity in patients with therapeutic problems in a psychiatric setting, a retrospective study.
Pharmacological research - 1 Apr 2017
Lloret-Linares Célia, Rollason Victoria, Lorenzini Kuntheavy Ing, Samer Caroline, Daali Youssef, Gex-Fabry Marianne, Aubry Jean-Michel, Desmeules Jules, Besson Marie
Abstract excerpt
OBJECTIVES: This retrospective study aimed to assess to what extent an adverse drug reaction (ADR), an abnormal therapeutic drug monitoring (TDM) or a non-response, was attributable to an abnormal cytochrome P450 activity in a psychiatric setting. METHOD: We collected the results of investigations performed in these situations related to psychotropic drugs between January 2005 and November 2014. Activities of...
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