Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Repressed PKCδ activation in glycodelin-expressing cells mediates resistance to phorbol ester and TGFβ.

Cellular signalling - 1 Oct 2016

Hautala Laura C, Koistinen Riitta, Koistinen Hannu

Abstract excerpt

Glycodelin is a glycoprotein mainly expressed in well-differentiated epithelial cells in reproductive tissues. In normal secretory endometrium, the expression of glycodelin is abundant and regulated by progesterone. In hormone-related cancers glycodelin expression is associated with well-differentiated tumors. We have previously found that glycodelin drives epithelial differentiation of HEC-1B endometrial...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Movement
Share to Cell Shape
Share to Enzyme Activation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Phosphorylation

Share to Protein Kinase C-delta

Share to RNA, Small Interfering

Share to Tetradecanoylphorbol Acetate

Share to Transforming Growth Factor beta

Source

Identifiers

PMID: 27373413
DOI: 10.1016/j.cellsig.2016.06.020

Genes

PDK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Repressed PKCδ activation in glycodelin-expressing cells mediates resistance to phorbol ester and TGFβ.PMID 27373413Read ↗

Promegestone (R5020) and Mifepristone (RU486) Both Function as Progestational Agonists of Human Glycodelin Gene Expression in Isolated Human Epithelial Cells1Semantic proximity Read ↗

Glycodelin: A Major Lipocalin Protein of the Reproductive Axis with Diverse Actions in Cell Recognition and DifferentiationSemantic proximity Read ↗

Ligand activated hPR modulates the glycodelin promoter activity through the Sp1 sites in human endometrial adenocarcinoma cells.Semantic proximity Read ↗

Antiprogestins inhibit growth and stimulate differentiation in the normal mammary gland.Semantic proximity Read ↗

Expression of glycodelin in human breast and breast cancer.Semantic proximity Read ↗

Genistein induces phenotypic reversion of endoglin deficiency in human prostate cancer cells.Semantic proximity Read ↗

Glycodelin in reproductive endocrinology and hormone-related cancerSemantic proximity Read ↗

Glycodelin expression associates with differential tumour phenotype and outcome in sporadic and familial non-BRCA1/2 breast cancer patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.