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Article

HBx-induced MiR-1269b in NF-κB dependent manner upregulates cell division cycle 40 homolog (CDC40) to promote proliferation and migration in hepatoma cells.

Journal of translational medicine - 27 Jun 2016

Kong Xiao-Xiao, Lv Yan-Ru, Shao Li-Ping, Nong Xiang-Yang, Zhang Guang-Ling, Zhang Yi, Fan Hong-Xia, Liu Min, Li Xin, Tang Hua

Abstract excerpt

BACKGROUND: Occurrence and progression of hepatocellular carcinoma (HCC) are associated with hepatitis B virus (HBV) infection. miR-1269b is up-regulated in HCC cells and tissues. However, the regulation of miR-1269b expression by HBV and the mechanism underlying the oncogenic activity of miR-1269b in HCC are unclear. METHODS: Reverse transcription quantitative PCR (RT-qPCR) was used to measure the expression of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27349221
DOI: 10.1186/s12967-016-0949-y
PMCID: PMC4924318

Genes

CDC40

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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