Article
The malaria parasite Plasmodium vivax exhibits greater genetic diversity than Plasmodium falciparum.
Nature genetics - 1 Sept 2012
Neafsey Daniel E, Galinsky Kevin, Jiang Rays H Y, Young Lauren, Sykes Sean M, Saif Sakina, Gujja Sharvari, Goldberg Jonathan M, Young Sarah, Zeng Qiandong, Chapman Sinéad B, Dash Aditya P, Anvikar Anupkumar R, Sutton Patrick L, Birren Bruce W, Escalante Ananias A, Barnwell John W, Carlton Jane M
Abstract excerpt
We sequenced and annotated the genomes of four P. vivax strains collected from disparate geographic locations, tripling the number of genome sequences available for this understudied parasite and providing the first genome-wide perspective of global variability in this species. We observe approximately twice as much SNP diversity among these isolates as we do among a comparable collection of isolates of P....
Topics
- Africa
- Americas
- Animals
- Asia
- Genetic Variation
- Geography
- Humans
- Malaria, Falciparum
- Malaria, Vivax
- Microsatellite Repeats