Article
Derivation of DM1 affected human embryonic stem cell line Genea067.
Stem cell research - 1 Mar 2016
Dumevska Biljana, Main Heather, McKernan Robert, Goel Divya, Schmidt Uli
Abstract excerpt
The Genea067 human embryonic stem cell line was derived from a donated, fully commercially consented ART blastocyst, carrying expansion of CTG repeats in the DMPK gene, indicative of Myotonic Dystrophy Type 1 (DM1). Following ICM outgrowth on inactivated human feeders, karyotype was confirmed as 46, XY and STR analysis demonstrated a male Allele pattern. The hESC line had pluripotent cell morphology, 85% of cells...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
