Article
Derivation of DM2 affected human embryonic stem cell line Genea066.
Stem cell research - 1 Mar 2016
Dumevska Biljana, Schaft Julia, McKernan Robert, Goel Divya, Schmidt Uli
Abstract excerpt
The Genea066 human embryonic stem cell line was derived from a donated, fully commercially consented ART blastocyst, carrying expansion of CCTG repeats in exon 1 of the ZNF9 gene, indicative of Myotonic Dystrophy Type 2 (DM2). Following ICM outgrowth on inactivated human feeders, karyotype was confirmed as 46, XY and STR analysis demonstrated a male Allele pattern. The hESC line had pluripotent cell morphology,...
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