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Derivation of Huntington Disease affected Genea091 human embryonic stem cell line.

Stem cell research - 1 Mar 2016

Dumevska Biljana, Schaft Julia, McKernan Robert, Hu Jesselyn, Schmidt Uli

Abstract excerpt

The Genea091 human embryonic stem cell line was derived from a donated, fully commercially consented ART blastocyst, carrying Htt gene CAG expansion of 40 repeats, indicative of Huntington Disease. Following ICM outgrowth on inactivated human feeders, karyotype was confirmed as 46, XX by CGH and STR analysis demonstrated a female Allele pattern. The hESC line had pluripotent cell morphology, 92% of cells...

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PMID: 27346013
DOI: 10.1016/j.scr.2016.02.022

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