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Article

The first European family with gastric adenocarcinoma and proximal polyposis of the stomach: case report and review of the literature.

Gastrointestinal endoscopy - 1 Oct 2016

Repak Rudolf, Kohoutova Darina, Podhola Miroslav, Rejchrt Stanislav, Minarik Marek, Benesova Lucie, Lesko Michal, Bures Jan

Abstract excerpt

BACKGROUND AND AIMS: Gastric adenocarcinoma and proximal polyposis of the stomach (GAPPS) has to date been recognized in only 8 families worldwide. Recently, different point mutations within the Ying Yang 1 (YY1) binding motif in promoter 1B of the APC gene were assigned as causal in 6 families with GAPPS. METHODS: We diagnosed GAPPS across 3 generations in a Czech white family. RESULTS: The proband's mother died...

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Source

Identifiers

PMID: 27343414
DOI: 10.1016/j.gie.2016.06.023

Genes

APC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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