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Article

The IL-17F sequence variant is associated with susceptibility to tuberculosis.

Gene - 15 Feb 2013

Peng Rong, Yue Jun, Han Min, Zhao Yanlin, Liu Lirong, Liang Li

Abstract excerpt

The interleukin (IL)-17 gene plays a key role in host defence against infections from microbes, including Mycobacterium tuberculosis. Genetic factors contribute to host defence. However, whether genetic variation in IL-17 is associated with altered susceptibility to tuberculosis is unknown. A total of 596 pulmonary tuberculosis (PTB) patients, 176 extra-pulmonary tuberculosis (EPTB) patients, and 622 control...

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Identifiers

PMID: 23219503
DOI: 10.1016/j.gene.2012.11.017

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