Article
Cardiac progenitor cell-derived exosomes prevent cardiomyocytes apoptosis through exosomal miR-21 by targeting PDCD4.
Cell death & disease - 23 Jun 2016
Xiao J, Pan Y, Li X H, Yang X Y, Feng Y L, Tan H H, Jiang L, Feng J, Yu X Y
Abstract excerpt
Cardiac progenitor cells derived from adult heart have emerged as one of the most promising stem cell types for cardiac protection and repair. Exosomes are known to mediate cell-cell communication by transporting cell-derived proteins and nucleic acids, including various microRNAs (miRNAs). Here we investigated the cardiac progenitor cell (CPC)-derived exosomal miRNAs on protecting myocardium under oxidative...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.