Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genomic analysis of nontypeable pneumococci causing invasive pneumococcal disease in South Africa, 2003-2013.

BMC genomics - 22 Jun 2016

Mohale Thabo, Wolter Nicole, Allam Mushal, Ndlangisa Kedibone, Crowther-Gibson Penny, du Plessis Mignon, von Gottberg Anne

Abstract excerpt

BACKGROUND: The capsular polysaccharide is the principal virulence factor of Streptococcus pneumoniae and a target for current pneumococcal vaccines. However, some pathogenic pneumococci are serologically nontypeable [nontypeable pneumococci (NTPn)]. Due to their relative rarity, NTPn are poorly characterized, and, as such, limited data exist which describe these organisms. We aimed to describe disease and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genome, Bacterial
Share to History, 21st Century

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Multilocus Sequence Typing

Share to Pneumococcal Infections

Share to Population Surveillance

Share to Serotyping

Share to South Africa

Share to Streptococcus pneumoniae

Source

Open in PubMed Open full text

Identifiers

PMID: 27334470
DOI: 10.1186/s12864-016-2808-x
PMCID: PMC4928513

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genomic analysis of nontypeable pneumococci causing invasive pneumococcal disease in South Africa, 2003-2013.PMID 27334470Read ↗

Population-based analysis of invasive nontypeable pneumococci reveals that most have defective capsule synthesis genes.Semantic proximity Read ↗

Molecular characterization of invasive capsule null Neisseria meningitidis in South Africa.Semantic proximity Read ↗

Population Snapshot of Streptococcus pneumoniae Causing Invasive Disease in South Africa Prior to Introduction of Pneumococcal Conjugate VaccinesSemantic proximity Read ↗

International genomic definition of pneumococcal lineages, to contextualise disease, antibiotic resistance and vaccine impactSemantic proximity Read ↗

Genomic relatedness of colonizing and invasive disease Klebsiella pneumoniae isolates in South African infantsSemantic proximity Read ↗

An unusual pneumococcal sequence type is the predominant cause of serotype 3 invasive disease in South Africa.Semantic proximity Read ↗

Comparative phylogenomics of Streptococcus pneumoniae isolated from invasive disease and nasopharyngeal carriage from West Africans.Semantic proximity Read ↗

Phylogenetic Analysis of Invasive Serotype 1 Pneumococcus in South Africa, 1989 to 2013.Semantic proximity Read ↗

Non-typeable pneumococci circulating in Portugal are of cps type NCC2 and have genomic features typical of encapsulated isolates.Semantic proximity Read ↗

A Streptococcus pneumoniae lineage usually associated with pneumococcal conjugate vaccine (PCV) serotypes is the most common cause of serotype 35B invasive disease in South Africa, following routine use of PCVSemantic proximity Read ↗

A Successful, Diverse Disease-Associated Lineage of Nontypeable Pneumococci That Has Lost the Capsular Biosynthesis LocusSemantic proximity Read ↗

Whole genomic comparative analysis of Streptococcus pneumoniae serotype 1 isolates causing invasive and non-invasive infections among children under 5 years in Casablanca, MoroccoSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.