Article
Population-based analysis of invasive nontypeable pneumococci reveals that most have defective capsule synthesis genes.
PloS one - 1 Jan 2014
Park In Ho, Geno K Aaron, Sherwood Logan K, Nahm Moon H, Beall Bernard
Abstract excerpt
Since nasopharyngeal carriage of pneumococcus precedes invasive pneumococcal disease, characteristics of carriage isolates could be incorrectly assumed to reflect those of invasive isolates. While most pneumococci express a capsular polysaccharide, nontypeable pneumococci are sometimes isolated. Carriage nontypeables tend to encode novel surface proteins in place of a capsular polysaccharide synthetic locus, the...
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