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Article

Non-typeable pneumococci circulating in Portugal are of cps type NCC2 and have genomic features typical of encapsulated isolates.

BMC genomics - 6 Oct 2014

Tavares Débora A, Simões Alexandra S, Bootsma Hester J, Hermans Peter Wm, de Lencastre Hermínia, Sá-Leão Raquel

Abstract excerpt

BACKGROUND: Pneumococcus is a major human pathogen and the polysaccharide capsule is considered its main virulence factor. Nevertheless, strains lacking a capsule, named non-typeable pneumococcus (NT), are maintained in nature and frequently colonise the human nasopharynx. Interest in these strains, not targeted by any of the currently available pneumococcal vaccines, has been rising as they seem to play an...

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Identifiers

PMID: 25283442
DOI: 10.1186/1471-2164-15-863
PMCID: PMC4200197

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