Article
Allergenicity and safety of recombinant human C1 esterase inhibitor in patients with allergy to rabbit or cow's milk.
The Journal of allergy and clinical immunology - 1 Aug 2016
van den Elzen Mignon T, van Os-Medendorp Harmieke, Röckmann-Helmbach Heike, van Hoffen Els, Lebens Ans F M, van Doorn Helma, Klemans Rob J B, Bruijnzeel-Koomen Carla A F M, Hack C Erik, Kaufman Leonard, Relan Anurag, Knulst André C
Abstract excerpt
BACKGROUND: Recombinant human C1 inhibitor (rhC1INH) for on-demand treatment of hereditary angioedema is purified from milk of transgenic rabbits. It contains low amounts (<0.002%) of host-related impurities, which could trigger hypersensitivity reactions in patients with rabbit allergy (RA) and/or cow's milk allergy (CMA). OBJECTIVE: This study is an assessment of allergenicity and safety of rhC1INH in patients...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.