Article
Haplotype analysis of the HFE gene among populations of Northern Eurasia, in patients with metabolic disorders or stomach cancer, and in long-lived people.
BMC genetics - 17 Jun 2016
Mikhailova S V, Babenko V N, Ivanoshchuk D E, Gubina M A, Maksimov V N, Solovjova I G, Voevoda M I
Abstract excerpt
BACKGROUND: Previously, it was shown that the HFE gene (associated with human hereditary hemochromatosis) has several haplotypes of intronic polymorphisms. Some haplotype frequencies are race specific and hence can be used in phylogenetic analysis. We assumed that analysis of Caucasoid patients-living now in Western Siberia and having diseases associated with dietary habits and metabolic rate-will allow us to...
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