Circular RNA expression profiling of granulosa cells in women of reproductive age with polycystic ovary syndrome

Abstract excerpt

PURPOSE: This study aimed to explore the expression profiles of circRNA in granulosa cells of women of reproductive age with polycystic ovary syndrome (PCOS). METHODS: Total RNA was isolated from granulosa cells of 15 women with PCOS and 15 body mass index- and age-matched healthy women (control). RNA sequencing was conducted on ribosomal-depleted RNA for circRNA expression profiling. The differential expression...

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