Article
Multi-objective shadow prices point at principles of metabolic regulation.
Bio Systems - 1 Aug 2016
Sajitz-Hermstein Max, Nikoloski Zoran
Abstract excerpt
Perturbations in environmental and intracellular conditions often lead to changes across all cellular layers, from transcription to metabolism. Regulatory mechanisms are key to mediating these changes to maintain homeostasis and to ensure viability. Since changes in metabolic reaction rates are partly due to perturbations in metabolite concentrations, it is expected that metabolites with large effect on those...
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