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Article

Genome-scale metabolic modelling when changes in environmental conditions affect biomass composition.

PLoS computational biology - 1 May 2021

Schulz Christian, Kumelj Tjasa, Karlsen Emil, Almaas Eivind

Abstract excerpt

Genome-scale metabolic modeling is an important tool in the study of metabolism by enhancing the collation of knowledge, interpretation of data, and prediction of metabolic capabilities. A frequent assumption in the use of genome-scale models is that the in vivo organism is evolved for optimal growth, where growth is represented by flux through a biomass objective function (BOF). While the specific composition of...

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Identifiers

PMID: 34029317
DOI: 10.1371/journal.pcbi.1008528
PMCID: PMC8177628

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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