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Autophagic Cell Death and Cancer

21 Feb 2014

Abstract excerpt

Programmed cell death (PCD) is a crucial process required for the normal development and physiology of metazoans. The three major mechanisms that induce PCD are called type I (apoptosis), type II (autophagic cell death), and type III (necrotic cell death). Dysfunctional PCD leads to diseases such as cancer and neurodegeneration. Although apoptosis is the most common form of PCD, recent studies have provided...

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PMID: 24566140
DOI: 10.3390/ijms15023145

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