Article
Proteolytic activation of both components of the cation stress-responsive Slt pathway in Aspergillus nidulans.
Molecular biology of the cell - 15 Aug 2016
Mellado Laura, Arst Herbert N, Espeso Eduardo A
Abstract excerpt
Tolerance of Aspergillus nidulans to alkalinity and elevated cation concentrations requires both SltA and SltB. Transcription factor SltA and the putative pseudokinase/protease signaling protein SltB comprise a regulatory pathway specific to filamentous fungi. In vivo, SltB is proteolytically cleaved into its two principal domains. Mutational analysis defines a chymotrypsin-like serine protease domain that...
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