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Article

Effect of antiviral treatment of chronic hepatitis C on the frequency of regulatory T cells, T-cell activation, and serum levels of TGF-beta.

APMIS : acta pathologica, microbiologica, et immunologica Scandinavica - 1 Aug 2016

Chalupa Pavel, Davidová Alžběta, Beran Ondřej, Arientová Simona, Boštík Pavel, Kapla Jaroslav, Kondělková Kateřina, Plíšek Stanislav, Holub Michal

Abstract excerpt

The aim was to analyze T-regulatory cells (Tregs), activated CD8(+) T cells, and transforming growth factor-beta (TGF)-β in hepatitis C patients. We enrolled 31 patients with chronic genotype 1 hepatitis C virus (HCV) infection, 30 seropositive persons with spontaneous HCV elimination, and 23 healthy volunteers. The patients were examined at the beginning of the interferon-alpha (IFN-α)-based therapy (baseline)...

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PMID: 27307383
DOI: 10.1111/apm.12561

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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