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Plasma membrane ion channels and epithelial to mesenchymal transition in cancer cells

12 Sept 2016

Abstract excerpt

A variety of studies have suggested that epithelial to mesenchymal transition (EMT) may be important in the progression of cancer in patients through metastasis and/or therapeutic resistance. A number of pathways have been investigated in EMT in cancer cells. Recently, changes in plasma membrane ion channel expression as a consequence of EMT have been reported. Other studies have identified specific ion channels...

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PMID: 27619258
DOI: 10.1530/erc-16-0334

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