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CD146 defines commitment of cultured annulus fibrosus cells to express a contractile phenotype

8 Jun 2016

Abstract excerpt

Characterization of cells is important for facilitating cell-based therapies for degenerative diseases of intervertebral discs. For this purpose, we analyzed mouse annulus fibrosus cells by flowcytometory to detect phenotypic change in their primary cultures. After examination of sixteen cell surface proteins, we focused on CD146 that solely increased during culture expansion. CD146 is known to be a marker for...

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Share to Musculoskeletal pain and rehabilitation
Share to Orthopaedic implants and arthroplasty
Share to Spine and Intervertebral Disc Pathology

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PMID: 27273299
DOI: 10.1002/jor.23326

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