Article
Genetic profiling of hepatocellular carcinoma using next-generation sequencing.
Journal of hepatology - 1 Nov 2016
Schulze Kornelius, Nault Jean-Charles, Villanueva Augusto
Abstract excerpt
Hepatocellular carcinoma (HCC) is a highly heterogeneous disease, both clinically and from a molecular standpoint. The advent of next-generation sequencing technologies has provided new opportunities to extensively analyze molecular defects in HCC samples. This has uncovered major cancer driver genes and associated oncogenic pathways operating in HCC. More sophisticated analyses of sequencing data have linked...
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